Abstract Background Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) and Cerebral Dopamine Neurotrophic Factor (CDNF) form an evolutionarily conserved family of neurotrophic factors.Orthologues for MANF/CDNF are the only neurotrophic factors as yet identified in invertebrates with conserved amino acid sequence.Previous studies indicate th
Hepatocellular carcinoma (HCC) is one of Barbecue the most common malignancies worldwide, and it has diverse etiologies with multiple mechanisms.The diagnosis of HCC typically occurs at advanced stages when there are limited therapeutic options.Hepatocarcinogenesis is considered a multistep process, and hepatic macrophages play a critical role in t
Abstract Finite element analysis is a powerful computational technique for augmenting Barbecue biomedical research, prosthetics design, and preoperative surgical assessment.However, the validity of biomechanical data obtained from finite element analysis is dependent on the quality of the preceding data processing.Until now, little information was
PURPOSEBreast cancer among Emirati patients is characterized by early-onset disease and later stages at presentation.Little is known about the germline genetic variants that may contribute to these observations.The goal of this study is to characterize the rate and implications of germline genetic variants among a cohort of Emirati patients at risk